Isatuximab with VRd for newly diagnosed multiple myeloma patients not eligible for transplant
Treatments studied
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.
This trial tests a combination of four drugs—isatuximab, bortezomib, lenalidomide, and dexamethasone—for people with newly diagnosed multiple myeloma who cannot have a stem cell transplant. The goal is to see if adding isatuximab helps control the cancer better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have been newly diagnosed with multiple myeloma and your doctor says you are not a candidate for a stem cell transplant
- Your blood counts are at a safe level: neutrophils (infection-fighting cells) ≥1.0, platelets ≥50
- Your kidney function is adequate (creatinine clearance ≥30 mL/min)
- Your liver function is normal (bilirubin ≤3 times the upper limit)
- You have not had a severe allergic reaction to isatuximab or any ingredients in the study drugs
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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