Comparing dapagliflozin vs pioglitazone for type 2 diabetes
Part of Hormones & metabolism clinical trials.
This study is testing two different diabetes pills—dapagliflozin or pioglitazone—in people with type 2 diabetes. The goal is to see which one works better when added to your current metformin and DPP-4 inhibitor. You may qualify if your blood sugar is not well controlled with your current medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have type 2 diabetes and are 19 or older.
- You have been taking the same doses of metformin and a DPP-4 inhibitor (like sitagliptin or linagliptin) for at least 8 weeks.
- Your A1c blood test is between 7.0% and 10.0%.
- Your body mass index (BMI) is between 18.5 and 40 kg/m².
- You do not have advanced heart failure, severe kidney disease, or a recent (within 6 months) heart attack or stroke.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new diabetes medicine called Enavogliflozin against an older drug, Pioglitazone, to see which works better for lowering blood sugar and improving heart health. If you have type 2 diabetes, take metformin plus another pill, and your A1C is between 7 and 10.5, this study may be an option for you.
This trial compares two diabetes medications, empagliflozin and glimepiride, added to your current treatment to see which is more effective and safe for managing blood sugar. It is for adults with type 2 diabetes who have already been on oral diabetes pills for at least 8 weeks.
This trial tests a combination of three common diabetes medications (metformin, an SGLT2 inhibitor, and a TZD) to see how well they work together and if they are safe. It may help people with type 2 diabetes who need better blood sugar control.
This trial tests two diabetes pills (pioglitazone and empagliflozin) to see if they can reduce liver fat in people with type 2 diabetes and fatty liver disease. It may help if your diabetes is not well controlled and you have a fatty liver confirmed by a special ultrasound scan.
This trial tests a medication called empagliflozin (a type 2 diabetes pill) to see how well it works in people with type 2 diabetes who have not taken any diabetes drugs for at least 8 weeks. If you qualify, you may receive the study drug and help researchers learn more about managing blood sugar.
This trial tests if adding pioglitazone to an SGLT2 inhibitor can lower blood sugar more and prevent high ketone levels in people with type 1 diabetes. It may help those who have poor blood sugar control despite insulin therapy.
Hear when a new Type2diabetes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.