Tranexamic acid and vitamin K for bleeding in cirrhosis
Part of Digestive system clinical trials.
This trial tests if giving tranexamic acid and vitamin K by injection can help control bleeding from the upper digestive tract in people with liver cirrhosis. It may offer a way to stop bleeding more quickly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with liver cirrhosis.
- You have active bleeding from your upper digestive tract (such as your stomach or esophagus).
- You are not allergic to tranexamic acid or vitamin K injection.
- You do not have a condition called DIC (a blood clotting disorder).
- You are not pregnant or breastfeeding and have no end-stage kidney disease.
- You have not had a recent blood clot (thromboembolic event).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether a newer type of blood thinner can safely prevent dangerous bleeding from enlarged veins in the food pipe (esophagus) in people with liver cirrhosis who also have blood clots in the portal vein. The goal is to reduce the risk of life-threatening bleeding while managing the clot.
This trial tests if giving albumin, a protein in the blood, can improve outcomes for patients with cirrhosis who have a specific type of bleeding from enlarged veins in the esophagus or stomach.
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This trial studies bleeding problems in people with advanced liver cirrhosis or liver cancer. It aims to improve understanding of when blood transfusions or treatments are needed.
This trial tests if tranexamic acid, a medicine that helps blood clot, can safely reduce bleeding during adult liver transplant surgery.
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