Studying megakaryocytes in sickle cell disease
Part of Blood & lymphatic, Genetic & congenital clinical trials.
This trial looks at the cells that help make platelets (megakaryocytes) in people with sickle cell disease. By comparing these cells when you are feeling well and during a pain crisis or chest syndrome, researchers hope to learn more about the condition and find better treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have sickle cell disease type SS or S-beta-zero thalassemia
- You are 18 years or older
- You are either at steady state (no crisis for at least 1 year), or currently having a pain crisis or acute chest syndrome
- You do not have a blood cancer or other blood disorder
- You do not have immune thrombocytopenia or take certain immune-suppressing or anti-inflammatory drugs
- You have not had a red blood cell exchange or transfusion in the last 3 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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