Clin2
NCT06889623Likely a fitRecruiting

Chemotherapy right after surgery for high-risk bladder cancer

NMIBC

Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.

This trial tests whether giving chemotherapy immediately after surgery can help people with high-risk, non-muscle-invasive bladder cancer. It aims to reduce the chance of the cancer coming back.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
72 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have high-risk bladder cancer that has not reached the muscle layer.
  • Your cancer includes features like high-grade tumors, tumor larger than 3 cm, multiple tumors, carcinoma in situ, or other concerning features.
  • You are in generally good health and can be followed for 2 years.
  • You have not had previous chemotherapy, immunotherapy, or radiation for bladder cancer.
  • You do not have other serious medical conditions like active infections or low blood cell counts.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06735287Recruiting
Bladder-sparing treatment for large bladder cancer

This trial tests a combination of chemotherapy and immunotherapy to treat large, non-invasive bladder cancer before and after surgery. It aims to avoid removing the bladder while still effectively treating the cancer.

Nanjing, Jiangsu
NCT06927128Not yet recruiting· Phase 2
Chemotherapy before surgery for high-risk upper urinary tract cancer

This trial tests whether giving chemotherapy before surgery can improve outcomes for people with high-risk cancer in the upper urinary tract (the tubes that carry urine from the kidneys to the bladder). The chemotherapy is given before the standard surgery to remove the affected kidney and ureter.

Shanghai, Shanghai Municipality
NCT07307456Recruiting· Phase 2
Toripalimab and BCG for high-risk bladder cancer

This trial tests a combination of two treatments after bladder tumor surgery: a drug called toripalimab (given through a vein) plus BCG therapy (given into the bladder) for people with high-risk non-muscle-invasive bladder cancer. The goal is to see if this combination can help prevent the cancer from coming back.

Shanghai, Shanghai Municipality
NCT06696794Recruiting· Phase 3
Testing mitomycin before surgery for high-risk bladder cancer

This trial tests whether giving mitomycin directly into the bladder before surgery can help people with high-risk non-muscle-invasive bladder cancer. The goal is to see if this approach is safe and effective at preventing cancer from coming back.

Wuhan, Hubei
NCT07690878Not yet recruiting· Phase 2
Chemotherapy before bladder removal surgery for muscle-invasive bladder cancer

This trial tests giving chemotherapy before surgery to remove the bladder, to see if it can improve outcomes for patients with muscle-invasive bladder cancer. The treatment is personalized based on a lab test of your tumor cells, which may help make the therapy more effective.

Nanjing, Jiangsu
NCT07053748Not yet recruiting
Chemo and radiation to keep the bladder in recurrent bladder cancer

This study looks at a treatment plan that uses a combination of chemotherapy and radiation to try to cure bladder cancer without removing the bladder. It is for people who have had bladder cancer come back several times or who did not get good results from BCG treatment.

Hear when a new NMIBC trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.