PET imaging study for Parkinson's and related conditions
Part of Brain & nervous system, Mental health clinical trials.
This trial uses a new imaging agent (like a dye) to see signs of Parkinson's disease in the brain. If you have Parkinson's or a related condition like Lewy body dementia or multiple system atrophy, this scan may help researchers better understand these illnesses.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 40 or older if you have Parkinson's, Lewy body dementia, or multiple system atrophy. Healthy volunteers must be 20 or older.
- Your weight must be between 110 and 220 pounds (50-100 kg), and BMI between 18 and 31.
- You must have a special brain scan (DAT scan) showing low dopamine function — either done recently or as part of the screening.
- If you are on Parkinson's medication, it must have been at a steady dose for at least 30 days before the study starts.
- You cannot have had any brain surgery, or treatments targeting the protein alpha-synuclein (like special vaccines or antibodies).
- For healthy volunteers, you must have no family history of Parkinson's or related conditions, no memory problems, and a normal brain MRI.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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