Tranexamic Acid After Knee Replacement Surgery
Part of Pain clinical trials.
This study tests whether taking tranexamic acid (a medicine that helps prevent bleeding) after total knee replacement can reduce pain and the need for strong painkillers. You would take the medicine for up to 7 days after surgery and answer a few daily questions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for a total knee replacement at Rush University Medical Center or a participating surgery center.
- You are willing to be randomly assigned to take a study medication for up to 7 days after surgery.
- You are willing to answer daily questions about pain, how well your knee works, and any pain medication you take.
- You have not had a blood clot, heart attack, or stroke in the past year.
- You do not take any blood-thinning medications besides aspirin, have no history of cancer or end-stage kidney disease on dialysis, and are not taking birth control pills.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests an experimental drug called BT-114143 to see if it reduces bleeding during and after total knee replacement surgery. It may be a good option for people with osteoarthritis who are having their first knee replacement.
This trial tests whether taking tranexamic acid (a medicine that helps blood clot) for several days after knee replacement surgery reduces bleeding and improves recovery. It may help patients who have a standard knee replacement and are not on blood thinners.
This trial tests if taking tranexamic acid (TXA) pills for a week after knee replacement surgery helps reduce bleeding and the need for blood transfusions. You may qualify if you are having a planned first-time knee replacement with spinal anesthesia and are already scheduled for standard care.
This trial tests if taking tranexamic acid (TXA) as a pill can reduce bleeding after total knee replacement surgery. It may help you if you have knee osteoarthritis and are scheduled for a first-time knee replacement.
This study tests whether a medicine called tranexamic acid (TXA) can reduce pain, improve movement, and lessen bleeding after hip or knee replacement surgery. It is for adults having their first joint replacement at St. Mary's Hospital.
This trial tests whether taking a longer course of a medication called TXA after joint replacement surgery can help prevent bleeding. TXA is a medicine that helps blood clot, and the goal is to see if taking it for more days reduces the need for blood transfusions.
Hear when a new Total Knee Arthroplasty trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.