Tranexamic acid after knee replacement to reduce bleeding and pain
Part of Pain clinical trials.
This study tests whether taking tranexamic acid for up to seven days after knee replacement surgery can reduce swelling, pain, and the need for pain pills. It may help you recover more comfortably after your operation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having a total knee replacement at Rush main hospital or a participating surgery center.
- You are willing to be randomly assigned to take the study medication for up to seven days after surgery.
- You are able to answer short daily questions about your pain, how well you can move, and how many pain pills you take.
- You have not had a blood clot, heart attack, or stroke in the past year.
- You are not taking blood thinners other than aspirin, and you do not have cancer or kidney failure requiring dialysis.
- You are not allergic to tranexamic acid, and you are not taking oral birth control pills.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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