Clin2
NCT07494032Likely a fitNot yet recruiting

Extended tranexamic acid after total knee replacement

Knee Arthropathy

Treatments studied

Part of Bones, joints & muscles clinical trials.

This study tests whether taking tranexamic acid (a medication that helps blood clot) for a few days after knee replacement surgery can reduce bleeding and the need for blood transfusions. It may help patients recover with fewer complications.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
350 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are scheduled for a total knee replacement (using spinal anesthesia).
  • You are 18 years or older.
  • You are not allergic to tranexamic acid or similar medications.
  • You are not currently taking blood thinners (other than low-dose aspirin).
  • You have no history of blood clots, kidney disease, or active cancer.
  • You are not pregnant, breastfeeding, or planning pregnancy during the treatment period.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06479161Recruiting· Phase 2
Oral tranexamic acid study for knee replacement patients

This trial tests if taking tranexamic acid (TXA) as a pill can reduce bleeding after total knee replacement surgery. It may help you if you have knee osteoarthritis and are scheduled for a first-time knee replacement.

Hartford, Connecticut
NCT06618820Enrolling by invitation· Phase 3
Extended tranexamic acid after knee replacement

This trial tests whether taking tranexamic acid (a medicine that helps blood clot) for several days after knee replacement surgery reduces bleeding and improves recovery. It may help patients who have a standard knee replacement and are not on blood thinners.

Germantown, Tennessee
NCT06894719Not yet recruiting· Phase 4
Tranexamic acid after knee replacement to reduce bleeding and pain

This study tests whether taking tranexamic acid for up to seven days after knee replacement surgery can reduce swelling, pain, and the need for pain pills. It may help you recover more comfortably after your operation.

NCT07685743Not yet recruiting· Phase 4
Extended tranexamic acid after knee or hip replacement

This study looks at whether taking tranexamic acid (a medicine that helps blood clot) by mouth for a few days after knee or hip replacement surgery can reduce blood loss and the need for transfusions. If you are having one of these surgeries for arthritis, this trial aims to improve your recovery.

NCT06832878Recruiting· Phase 4
Tranexamic Acid Pills After Hip Replacement

This study tests whether taking tranexamic acid (TXA) pills after hip replacement can reduce bleeding and the need for blood transfusions. It is for people having a first-time hip replacement due to severe arthritis who stay one night in the hospital.

Scottsdale, Arizona
NCT07853885Not yet recruiting· Phase 4
Tranexamic acid in bone to reduce bleeding during knee replacement

This study tests whether putting tranexamic acid (a medicine that helps blood clot) directly into the bone during knee replacement surgery can reduce blood loss. It may help people recover with less need for blood transfusions.

Kunming, Yunnan

Hear when a new Knee Arthropathy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.