Low-dose blood thinner for older stroke survivors with atrial fibrillation
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether a lower dose of the blood thinner edoxaban can safely prevent another stroke in people aged 80 or older who have atrial fibrillation (an irregular heartbeat) and have already had a stroke or mini-stroke. It may be an option for those at higher risk of bleeding.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 80 years old or older.
- You have been diagnosed with atrial fibrillation (an irregular heartbeat).
- You have had a stroke or a transient ischemic attack (often called a mini-stroke) in the past.
- You have at least one of these bleeding risk factors: low body weight (under 60 kg), reduced kidney function, a history of major or stomach bleeding, or you are taking certain medications that increase bleeding risk (like aspirin, clopidogrel, or some pain relievers).
- You have not taken certain blood thinners recently (warfarin within the last month, or heparin or other direct oral anticoagulants within the last week).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two blood-thinning medicines, edoxaban and apixaban, to see which one is better at preventing strokes and bleeding in people who have both atrial fibrillation and coronary artery disease. If you're eligible, you may receive one of these standard treatments, and the trial could help find the safer option.
This trial tests a new medication to prevent strokes and blood clots in people with atrial fibrillation (an irregular heartbeat) who cannot safely take standard blood thinners. The drug works by blocking a different clotting factor, which may lower bleeding risks.
This study tests whether taking a blood thinner after a stroke is safe and helpful for people who have atrial fibrillation (an irregular heartbeat) and have had a bleeding stroke in the past. It aims to prevent future strokes while managing the risk of another brain bleed.
This trial tests whether switching to a different type of blood thinner is better than continuing the same type after a stroke. It aims to find the safest way to prevent another stroke in people with atrial fibrillation.
This trial tests whether starting blood thinners soon after a procedure to remove a blood clot from the brain can safely prevent another stroke in people who have atrial fibrillation. Participation is for those who had a severe stroke, received the clot-removal procedure, and are medically stable afterward.
This study tests the safety of a new blood thinner for people with atrial fibrillation (AFib) who need long-term stroke prevention. If you qualify, the study will compare this medication to standard anticoagulation therapy.
Hear when a new Elderly trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.