Anti-inflammatory vs. Prolotherapy for Knee Osteoarthritis
Part of Bones, joints & muscles clinical trials.
This study tests whether anti-inflammatory medications or dextrose prolotherapy (sugar water injections) can reduce knee pain and improve function in people with knee osteoarthritis. If you are a military healthcare beneficiary with moderate to severe knee pain, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a Department of Defense healthcare beneficiary receiving care at the David Grant Medical Center.
- You are between 45 and 75 years old.
- You have knee osteoarthritis diagnosed by a doctor, with X-ray showing moderate arthritis (grade 2 or 3).
- You have had moderate to severe knee pain for at least 3 months (pain score of 4 or higher out of 10).
- You have not had knee surgery (like replacement or meniscus repair) and no knee injection in the last 3 months.
- You are not pregnant or breastfeeding, and you have no allergy to dextrose, lidocaine, or sulfites.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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