Clin2
NCT06915753Possibly a fitRecruiting

TYRA-430 for advanced liver cancer and other solid tumors

Metastatic Hepatocellular CarcinomaSolid TumorsSolid Tumor, AdultFGFR Gene AmplificationFGFR Gene AlterationsFGFR3 Gene AlterationFGFR3 Gene MutationAdvanced Solid Tumors

Part of Cancer, Digestive system clinical trials.

This trial tests an oral drug called TYRA-430 for people with advanced liver cancer (HCC) or other solid tumors that have changes in the FGF/FGFR pathway. It aims to see how safe the drug is and whether it can shrink tumors or slow cancer growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You need to have advanced liver cancer (HCC) or another solid tumor with a specific change in the FGF/FGFR pathway.
  • You must have already had at least one standard treatment for your cancer.
  • You should be able to swallow pills and have good organ function (like liver and kidneys).
  • You cannot have serious heart problems, untreated brain tumors, or certain stomach issues that affect swallowing.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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