Reduced dose prasugrel alone after stent placement
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests if a lower dose of prasugrel, taken alone (without aspirin), is safe and works well for people who have had a stent placed for chest pain or a heart attack. It might be an option for those who need to simplify their medication routine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had a heart attack or unstable angina (acute coronary syndrome) or stable chest pain (chronic coronary syndrome).
- You had a successful stent placement (PCI).
- You are not allergic to prasugrel and do not have active bleeding or severe liver disease.
- You are not taking blood thinners (like warfarin or apixaban) and do not need to keep taking aspirin plus another blood thinner.
- You are not pregnant or breastfeeding.
- You are not taking certain medicines for other conditions (like cyclophosphamide or efavirenz).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests switching from a standard blood thinner (clopidogrel) to a lower dose of a stronger one (prasugrel) in people who have had a stent placed and are at high risk for both bleeding and heart problems. The goal is to see if the switch better prevents clots while keeping bleeding risks low.
This trial tests if a very short course of dual antiplatelet therapy (two blood thinners) after getting a stent is safe and effective for patients aged 65 and older. The goal is to reduce bleeding risks while still preventing heart attacks.
This study compares two ways to manage blood thinners after a stent. It tests whether switching from stronger drugs (prasugrel or ticagrelor) to clopidogrel is safe and effective for long-term heart protection.
This trial compares two ways of using anti-platelet (blood-thinner) medicines after a specific kind of heart attack (STEMI) treated with a stent. It aims to see if switching sooner to one medicine (instead of two for longer) works just as well and may reduce risks.
This trial looks at whether using clopidogrel by itself (without aspirin) works for people after a new drug-eluting stent, based on a blood test of how your body processes the drug. It may help reduce “extra blood-thinning” if you have a certain genetic type that responds well to clopidogrel.
This trial is testing whether lowering the dose of your current blood thinner or switching to a different one (clopidogrel) is safer and works just as well after you've had a stent placed. It's designed for people who are already on two blood thinners and are doing well.
Hear when a new Coronary Arterial Disease (CAD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.