Clinical trials
Coronary Arterial Disease (CAD) clinical trials
Below are recruiting coronary arterial disease (cad) clinical trials, each written for real people, not researchers. We’re tracking 192 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07777341Recruiting
Red grape juice and heart health in men
This study tests whether drinking red grape juice every day for a period can improve metabolism in men with coronary artery disease (blocked or narrowed heart arteries). If you have heart disease and are not diabetic, this could be a simple dietary addition to support your heart health.
São Paulo, São PauloAges 46–69 - NCT06959524Recruiting
Drug-coated balloon for new coronary blockages
This trial is testing a special balloon coated with medication to treat newly formed blockages in the heart's arteries. The medication may help keep the artery open after the balloon opens it during a standard procedure.
Jonesboro, ArkansasAges 18 years+ - NCT07691502Recruiting
Using CT scans before angioplasty to plan treatment
This trial tests if using a special heart CT scan (CCTA with FFRCT) before a planned angioplasty can help doctors better plan where to place stents. You may be eligible if you have a narrowing in one or two heart arteries that haven't been treated before.
Minneapolis, MinnesotaAges 22 years+ - NCT06143332Recruiting
Aerobic exercise after a heart attack: which type works best?
This study compares two types of aerobic exercise (steady vs. interval) to see which one improves heart health more for people who have recently had a heart attack or procedure. If you've completed a stress test and been cleared for exercise, you may be able to join.
London, OntarioAges 18 years+ - NCT07314138Recruiting
Comparing two minimally invasive heart bypass surgeries for three-vessel disease
This trial compares two types of heart bypass surgery for people with blockages in three main heart arteries. It tests a hybrid approach that combines a small incision bypass with a stent, versus a standard off-pump bypass. This may mean less recovery time for some patients.
Leuven, Vlaams BrabantAges 18–85 - NCT05698732Recruiting
Coroflex stent study for selected small heart artery blockages
This trial studies a new heart stent (called Coroflex ISAR NEO) for people who need a procedure to open a narrowed coronary artery. It may help improve long-term results for patients with certain small, short blockages who can safely take the required blood-thinning medicines.
Aix-en-ProvenceAges 18 years+ - NCT07510438Recruiting
Pulse IVL treatment for hardened arteries in the heart
This trial tests a new device that uses sound waves to break up calcium deposits in heart arteries, making them easier to open. It may help people with coronary artery disease who have not had prior stents or recent heart attacks.
Sydney, New South WalesAges 18 years+ - NCT06374498Enrolling by invitation
Looking inside heart arteries to improve stent placement
This study tests a new imaging technique to help doctors see inside your heart arteries during a stent procedure. It may help guide treatment and improve outcomes for people with heart disease.
Boston, MassachusettsAges 18 years+ - NCT07753200RecruitingPhase 4
Comparing two blood thinners for atrial fibrillation and heart disease
This study compares two blood-thinning medicines, edoxaban and apixaban, to see which one is better at preventing strokes and bleeding in people who have both atrial fibrillation and coronary artery disease. If you're eligible, you may receive one of these standard treatments, and the trial could help find the safer option.
SeoulAges 19 years+ - NCT07646444Recruiting
Study of OPN Balloon for Opening Hardened Heart Vessel Blockages
This is a follow-up study of patients who have already had a heart procedure using a special balloon (OPN balloon) to open calcified (hardened) blockages in heart arteries. Researchers will review records to see how well this balloon works and how patients recover.
Minneapolis, MinnesotaAges 18 years+ - NCT06916520RecruitingPhase 4
Reduced dose prasugrel alone after stent placement
This trial tests if a lower dose of prasugrel, taken alone (without aspirin), is safe and works well for people who have had a stent placed for chest pain or a heart attack. It might be an option for those who need to simplify their medication routine.
AmsterdamAges 18 years+ - NCT06794359Enrolling by invitation
Comparing minimally invasive vs. traditional bypass for multi-vessel heart disease
This study compares two types of heart bypass surgery for people with blockages in multiple heart arteries: a newer, less invasive technique (minimally invasive CABG) versus the traditional open-chest approach. It aims to see which approach leads to better recovery and outcomes.
São Paulo, São PauloAges 18 years+ - NCT07159087Enrolling by invitation
New drug balloon for re-narrowed stents
This trial tests a new drug-coated balloon (Genoss SCB) versus an existing one (SeQuent Please NEO) for people whose heart stents have re-narrowed. It aims to see which balloon better keeps the artery open.
Gyeonggi-doAges 19 years+ - NCT07093788Recruiting
Comparing two ways to treat hard calcium in heart arteries
This trial tests two methods for breaking up heavy calcium buildup in heart arteries before placing a stent. It compares a specialized high-pressure balloon to a device that uses shockwaves.
Lianyungang, JiangsuAges 18–80 - NCT07195149RecruitingPhase 3
Aspirin dose comparison after bypass surgery
This trial tests whether a lower dose of aspirin combined with another blood thinner (prasugrel) after bypass surgery is as safe and effective as a higher dose. It is for people with stable heart disease who are scheduled for bypass surgery and have not had a recent heart attack.
BialystokAges 18 years+ - NCT07172620Recruiting
Heart bypass surgery without clamping the aorta
This study tests a special technique for heart bypass surgery that avoids clamping the aorta. It may help people with hardened arteries in the aorta who need bypass surgery but are not good candidates for standard clamping.
Beijing, Beijing MunicipalityAges Any age - NCT07232069RecruitingPhase 3
Early heart disease trial for women and men with mild plaque buildup
This trial tests whether two medicines, a statin and colchicine, can slow or stop early heart artery plaque from growing in people who have mild plaque but no heart disease symptoms yet. It uses special CT scans to measure plaque over 2 years.
Birmingham, AlabamaAges 30–60 - NCT06969547Recruiting
Heart muscle coordination and microvessel function SPECT study
This study uses a special heart scan (SPECT) to look at how well the heart muscle is squeezing and how well the tiny blood vessels in the heart are working. It may help doctors understand why some people have chest pain even when their main arteries are not blocked.
TomskAges 18–75 - NCT07041359RecruitingPhase 4
Traditional Chinese medicine for elderly heart disease patients with ongoing symptoms
This trial tests whether traditional Chinese medicine can help elderly patients with coronary heart disease who still have chest pain or discomfort despite standard treatments. It focuses on those who cannot have or have not fully benefited from procedures like stents or bypass surgery.
Beijing, Beijing MunicipalityAges 75–90 - NCT07068776Recruiting
Shockwave therapy to improve leg wound healing after bypass surgery
This trial tests if using shockwave therapy on leg veins during coronary artery bypass surgery can help the leg wound heal better. It may be a good fit if you need 2 or more vein grafts and have stable kidney function.
Innsbruck, TyrolAges 18 years+ - NCT07696533Recruiting
Comparing two imaging tests for chronic coronary syndrome
This trial sees if a carotid ultrasound is as good as a CT calcium score to detect heart disease in people with chest pain. It may help avoid more expensive or less available scans.
HarrowAges 18 years+ - NCT04545112Enrolling by invitation
Testing a new heart bypass graft in people needing multi-vessel CABG
This study tests a new way to connect a bypass graft during heart bypass surgery for people with blocked heart arteries. The goal is to see if the new graft can be safely placed and works well enough to improve outcomes compared with the standard approach.
LeuvenAges 18 years+ - NCT06822712Recruiting
Sirolimus-coated balloon for heart artery branch blockages
This trial tests a new balloon coated with sirolimus (a drug that helps prevent re-blockage) for treating blocked arteries at branch points (bifurcations) in the heart. If you have a blocked artery at a branch point, this study may offer a way to treat the side branch without placing a stent there.
Lanzhou, GansuAges 18–80 - NCT07341932Recruiting
Heart mapping test for stable coronary artery disease treatment
This trial tests whether a non-invasive heart mapping technique can guide treatment for stable coronary artery disease, potentially avoiding more expensive or invasive tests. You may join if you have stable angina and a blockage of 50-90% in a major heart artery.
Beijing, Beijing MunicipalityAges 18–80
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Coronary Arterial Disease (CAD) trials by city
Studies with a site in or near these metro areas.
Coronary Arterial Disease (CAD) trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for coronary arterial disease (cad)?
- Yes. Clin2 currently lists 192 recruiting coronary arterial disease (cad) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary arterial disease (cad) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary arterial disease (cad) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.