Clin2
NCT06925048Possibly a fitNot yet recruiting

Combination treatment for advanced lung cancer

Non-Small Cell Lung CancerJAK InhibitorImmunology

Part of Cancer, Lungs & breathing clinical trials.

This study tests a new pill combined with immunotherapy for people with advanced non-small cell lung cancer that has not been treated or has stopped responding to previous immunotherapy. The goal is to see if the combination is safe and helps shrink tumors.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
86 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have advanced non-small cell lung cancer (stage IIIB/IIIC or stage IV) that cannot be removed with surgery and is not suitable for chemotherapy and radiation.
  • You have not had any treatment for your lung cancer, OR you had immunotherapy before and it worked for a while (at least 6 months) but then the cancer started growing again.
  • You have at least one tumor that can be measured and a tumor that can be biopsied (a small sample taken) safely.
  • You are in good enough health to carry out daily activities (ECOG score 0 or 1).
  • Your blood counts and organ function (kidney, liver) are within acceptable ranges.
  • You do not have certain genetic mutations in your tumor (EGFR, ALK, or ROS1).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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