Study of AK146D1 for advanced solid tumors
Treatments studied
Part of Cancer clinical trials.
This study tests an experimental drug (AK146D1) for people with advanced solid tumors that are no longer responding to standard treatments. The goal is to see if it is safe and effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 75 years old
- Your advanced cancer has grown despite standard treatments, or no standard treatment exists
- You have at least one tumor that can be measured on scans
- Your overall health and daily activity level are good (ECOG 0 or 1)
- Your major organs (liver, kidneys, bone marrow) are working well enough
- You have not had a Trop-2, Nectin-4, or topoisomerase I inhibitor drug before
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a new drug called AK146D1 for people with advanced solid tumors that have not responded to standard treatments or no longer work. The goal is to see if it is safe and effective.
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This trial tests a new drug called AK138D1 for people with advanced solid tumors. It aims to see if the drug is safe and how well it works, especially for tumors that haven't been treated with HER3-targeted therapy before.
This is a Phase 1 study testing a new drug called AK150 in patients with advanced cancer that has spread or hasn't responded well to standard treatments. The goal is to find the right dose and see how well it works.
This trial tests a combination of two experimental drugs, AK146D1 and AK112, for people with advanced non-small cell lung cancer that cannot be removed by surgery or treated with standard chemo-radiation. It aims to find out if this combination can shrink tumors or slow cancer growth.
This trial tests a new drug called AK131 for people with advanced solid tumors that have stopped responding to standard treatments. It aims to see if the drug is safe and can help slow or shrink the cancer.
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