Genes and painkiller response for tooth pain
Treatments studied
Part of Pain clinical trials.
This trial tests whether your genes affect how well a common painkiller (NSAID) works for tooth pain after a root canal procedure. It may help find the best pain relief for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have a lower back tooth (molar) that is still alive and is causing pain (symptomatic apical periodontitis).
- Your pain level is greater than 50 on a 0–100 scale.
- You are not pregnant and have not taken any painkillers in the last 12 hours.
- You have no serious health conditions, allergies, genetic disorders, or other dental problems listed in the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This research study examines how your genes affect pain and inflammation when you have a painful tooth that needs root canal treatment. By studying these responses, researchers hope to better understand why some people experience different levels of pain during dental procedures.
This trial tests whether a combination of pain medicines given before a root canal can lower pain afterward. It is for people who have moderate to severe tooth pain and are healthy enough for standard treatment.
This trial compares two different ways of cleaning and shaping the inside of a tooth (root canal) to see which one causes less pain afterward. It is for people with a specific type of tooth infection in a lower back molar.
This study compares two types of medication placed inside a tooth after root canal treatment to see which one reduces pain and swelling better. It may help people with a dead nerve in a back tooth who have no current pain but have an infection around the root.
This study tests two different pain medicines (trypsin-chymotrypsin and naproxen sodium) to see which one works better for pain after a root canal. It may help you if you need a root canal and are generally healthy.
This trial tests whether rinsing the tooth with either tramadol (a pain reliever) or dexamethasone (a steroid) after a root canal reduces pain better. It is for people with a single-rooted tooth that has a very painful, inflamed nerve.
Hear when a new Postoperative Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.