Clin2
NCT07036237Possibly a fitEnrolling by invitation

Comparing pain relief rinses after root canal

Post-endodontic Pain

Part of Mouth & dental, Pain clinical trials.

This trial tests whether rinsing the tooth with either tramadol (a pain reliever) or dexamethasone (a steroid) after a root canal reduces pain better. It is for people with a single-rooted tooth that has a very painful, inflamed nerve.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
105 people
Ages
18 years to 50 years
Study type
Interventional

Who can take part

  • You are between 18 and 50 years old.
  • You are generally healthy (ASA 1 or 2) — meaning no serious medical conditions or only mild, well-controlled ones.
  • The tooth that hurts is a single-rooted tooth with a very painful, inflamed nerve (symptomatic irreversible pulpitis).
  • You have not taken any pain medication in the last 12 hours.
  • You are not pregnant or breastfeeding.
  • You are not allergic to tramadol or dexamethasone.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06980870Recruiting· Phase 2
Pain medicine before root canal for less discomfort

This study tests whether taking ibuprofen or dexamethasone before a root canal can help reduce pain afterward. It's for people with a painful, inflamed tooth nerve who haven't already taken pain medicine for it.

Rawalpindi
NCT07400471Recruiting· Early Phase 1
Pain relief before root canal: a medicine combination

This trial tests whether a combination of pain medicines given before a root canal can lower pain afterward. It is for people who have moderate to severe tooth pain and are healthy enough for standard treatment.

Chittagong, Chattogram
NCT06562816Recruiting· Phase 4
Comparing two pain relievers after root canal treatment

This study tests two different pain medicines (trypsin-chymotrypsin and naproxen sodium) to see which one works better for pain after a root canal. It may help you if you need a root canal and are generally healthy.

Karachi, Sindh
NCT07264829Not yet recruiting
Cold therapy for reducing pain during root canal treatment

This trial is testing two cold-therapy techniques applied directly to the tooth nerve to see which one better reduces pain during a root canal treatment. It aims to make the anesthesia work faster and more effectively, so you feel less discomfort during the procedure.

Karachi, Sindh
NCT07738302Not yet recruiting
Cryotherapy and dexamethasone for pain after root canal

This study tests whether applying cold therapy or a steroid medicine inside the tooth after a root canal can reduce pain after the procedure. If you have a painful, infected tooth needing a root canal, this might help you feel more comfortable afterward.

NCT06894069Not yet recruiting· Early Phase 1
Steroid inside a root canal for less tooth pain

This study looks at whether putting a common steroid medicine (dexamethasone) inside the tooth during a root canal can reduce pain after the procedure. If you have a painful tooth with an inflamed nerve, this treatment might help you feel better faster.

Hear when a new Post Endodontic Pain trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.