Clin2
NCT06940518Possibly a fitRecruiting

Ivonescimab for advanced clear cell kidney cancer

IvonescimabClear Cell Renal Carcinoma

Treatments studied

Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.

This trial tests a new drug, ivonescimab, for people with advanced clear cell kidney cancer that has grown after at least one prior treatment. It may help shrink tumors or slow the cancer's growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
40 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have advanced clear cell kidney cancer that has spread.
  • You have had at least one prior treatment for advanced disease, including a drug like Keytruda or Opdivo that targets PD-1/PD-L1.
  • Your cancer has gotten worse after your last treatment.
  • You have at least one tumor that can be measured on scans.
  • You are able to perform daily activities with little or no help (ECOG 0-2).
  • You are 18 years or older.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07743138Not yet recruiting· Phase 2
Ivonescimab for advanced adrenal gland tumors

This study tests a new drug called ivonescimab for people with advanced adrenal gland tumors (adrenocortical carcinoma or pheochromocytoma/paraganglioma) that cannot be removed with surgery. The goal is to see if the drug can reduce or stop the growth of the tumors.

Houston, Texas
NCT06959550Recruiting· Phase 2
Ivonescimab for previously treated metastatic colorectal cancer

This trial tests a new drug called ivonescimab, which is a bispecific antibody that targets both PD-1 and VEGF. It is for people with metastatic colorectal cancer who have already tried standard treatments and may or may not have received immunotherapy before, depending on their tumor type.

Houston, Texas
NCT06567314Recruiting· Phase 2
Study of Ivonescimab for advanced skin or prostate cancer

This study tests a new immunotherapy medicine, ivonescimab, in people with advanced skin cancer or advanced prostate cancer. It looks at how safe and effective the drug is.

Houston, Texas
NCT07401875Recruiting· Phase 1
New drug plus immunotherapy for advanced kidney cancer

This trial tests a new oral drug (HC-7366) combined with two immunotherapy drugs (nivolumab and ipilimumab) for people with advanced clear cell kidney cancer. The goal is to see if adding this new drug can help shrink tumors or slow the cancer's growth.

Houston, Texas
NCT07226544Recruiting· Phase 2
Ivonescimab before surgery for high-risk kidney cancer

This trial tests giving the drug ivonescimab before surgery for patients with high-risk clear cell kidney cancer. The goal is to see if it can help shrink the tumor and improve outcomes.

Duarte, California
NCT06925724Recruiting· Phase 2
Ivonescimab for advanced endometrial or cervical cancer

This study tests a new drug called ivonescimab for people with advanced endometrial or cervical cancer that has progressed after standard platinum-based chemotherapy. Ivonescimab is an investigational immunotherapy that may help your immune system fight the cancer.

Basking Ridge, New Jersey

Hear when a new Ivonescimab trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.