Freezing nerves for hip or knee replacement pain
Part of Bones, joints & muscles, Pain clinical trials.
This study tests if freezing nerves (cryoneurolysis) before hip or knee replacement surgery can reduce pain and opioid use. It is for people already scheduled for surgery who take daily pain medication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for hip or knee replacement surgery due to arthritis.
- You have been taking opioid pain medicine every day for at least one month.
- You are 18 years or older.
- You live within 1 hour of the study hospital, or can travel there for visits.
- You can speak and understand English.
- You have no allergies to numbing medicines (like those used at the dentist).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests if freezing a nerve near the shoulder before surgery can reduce pain after a reverse total shoulder replacement. It may help you recover with less discomfort.
This trial tests a cold therapy on nerves before knee replacement to reduce pain. It may help you recover with less discomfort after surgery.
This trial tests a cold treatment called cryoneurolysis to reduce pain after knee replacement surgery. It may help you move better and use less pain medication.
This study watches how well a freezing procedure works for chronic pain over 6 to 12 months. Your doctor thinks this procedure could help your pain, and the study simply tracks your recovery through questionnaires to help doctors understand if it works.
This study looks at freezing a nerve before ACL surgery to help reduce the amount of strong pain medicine you need afterward. If you're having ACL reconstruction with your own tendon and haven't been using opioids regularly, you may be able to join.
This study tests whether applying cold therapy (cryotherapy) after knee replacement surgery helps patients need fewer opioid pain medications than standard care alone. If cryotherapy works, it could help you manage pain more safely after surgery.
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