Freezing nerves for pain relief before hip or knee replacement
Part of Bones, joints & muscles, Pain clinical trials.
This study tests a freezing treatment (cryoneurolysis) to numb the nerves around your hip or knee before surgery. The goal is to reduce pain and make the wait for surgery more comfortable.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are waiting to have a hip or knee replacement surgery and have already agreed to it.
- Your joint pain is from osteoarthritis (wear-and-tear arthritis).
- You have been taking opioid pain medication (like oxycodone or morphine) every day for at least a month.
- You are older than 18 and can speak and understand English.
- You live within about an hour of the hospital or are willing to travel there for the procedure and follow-up.
- You are not allergic to local anesthetics (numbing medicines), and do not have conditions that would make the freezing procedure unsafe (like bleeding problems or cold allergies).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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