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NCT06944457Possibly a fitRecruiting

Safety Study of MPD-1 for Advanced Solid Tumors

CancerSolid Tumor CancerBiomarkers

Part of Cancer clinical trials.

This trial tests a new drug called MPD-1 for people with advanced solid tumors that have not responded to standard treatments. It focuses on patients with specific genetic changes (KRAS mutation or PTEN loss) to see if the drug is safe and how the body processes it.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
24 people
Ages
19 years to 75 years
Study type
Interventional

Who can take part

  • You are between 19 and 75 years old.
  • You have advanced solid tumor that has spread or cannot be removed, and standard treatments no longer work or were not enough.
  • Your tumor has a KRAS mutation or PTEN loss, confirmed by a lab test before screening.
  • You have never taken anthracycline or anthracene drugs (a type of chemotherapy).
  • You have at least one tumor that can be measured or assessed on scans.
  • Your blood counts, kidney, and liver function are within certain acceptable ranges (specific tests will be done).
  • Your overall health is good (ECOG score 0 or 1), and you are expected to live at least 12 more weeks.
  • You have recovered from side effects of previous treatments (except hair loss or mild nerve issues).
  • You agree to use effective contraception if you or your partner could become pregnant, for at least 24 weeks after the last dose.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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