Clin2
NCT06945510Possibly a fitNot yet recruiting

Antibiotic guidance for severe infections in intensive care

Sepsis

Part of Infections clinical trials.

This trial tests whether using a blood test called procalcitonin (PCT) can help doctors decide when to use antibiotics for critically ill patients in the intensive care unit (ICU). It may help reduce unnecessary antibiotics and improve care.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
800 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have a suspected or confirmed bacterial infection.
  • You have been in the intensive care unit (ICU) for more than 3 days.
  • Your PCT blood level is not consistently below 0.5 ng/mL during your hospital stay.
  • You are not pregnant and do not have certain conditions that require long-term antibiotics (like heart infections or bone infections).
  • You have not had a bone marrow transplant or chemotherapy that lowered your white blood cell count to very low levels.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07211620Recruiting
Using procalcitonin blood tests to guide antibiotic decisions in the ICU

This study compares two ways of using a blood test called procalcitonin to decide when to start antibiotics in critically ill patients with a new infection. The goal is to reduce unnecessary antibiotic use while still effectively treating infections.

Budapest
NCT07874698Not yet recruiting
Using genetic tests to guide treatment for suspected sepsis

This trial tests whether a quick genetic test can help doctors choose the right treatment for patients with a suspected severe infection (sepsis) more quickly. The goal is to improve recovery by personalizing care based on your body's response.

NCT07813767Recruiting· Phase 3
Early antibiotic treatment guided by a blood test to prevent severe infection

This study tests whether giving an early antibiotic (meropenem) based on a new blood test (PSP) can prevent serious infections (sepsis) in people who come to the emergency department with signs of infection. The goal is to find out if this approach helps them get better faster and avoid more severe illness.

Athens, Attica
NCT06253325Recruiting
Early detection of patients at risk for sepsis

This trial is looking for patients who have an infection and are showing early signs of getting sicker, like a high warning score. It aims to find out if doctors can identify those at risk of sepsis sooner so they can start treatment earlier.

Southampton, Hampshire
NCT07796386Not yet recruiting
Blood test to predict sepsis in ICU patients

This study looks at whether a simple blood test can help doctors find out if ICU patients with infections are likely to develop sepsis within the next 48 hours. If you join, the researchers will measure a protein in your blood and follow you to see if you get sepsis.

Guangzhou, Guangdong
NCT06103500Recruiting
Helping choose the right antibiotic for sepsis

This trial tests a computer tool to help doctors choose the right antibiotic for sepsis early on. It may help improve treatment by providing personalized recommendations based on your condition.

Mississauga, Ontario

Hear when a new Sepsis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.