New triple therapy for newly diagnosed type 2 diabetes
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial tests a new triple-combination therapy (three diabetes medicines together) for people with newly diagnosed type 2 diabetes who are overweight. The goal is to see if this combination can better control blood sugar and help with weight management.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You were diagnosed with type 2 diabetes within the last year, or you have not taken diabetes medications for more than 3 months.
- Your A1c level (a 3-month average blood sugar test) is between 6.5% and 9.0%.
- Your BMI is 24 or higher (meaning you are overweight or obese).
- You do not have severe kidney disease (eGFR below 20), advanced heart failure, or certain other conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new three-medicine combination to help control blood sugar in people newly diagnosed with type 2 diabetes who haven't been treated yet. The goal is to find out if this combination works better than current options.
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
This trial tests if newer diabetes medications can reduce heart risk and help achieve diabetes remission in people newly diagnosed with type 2 diabetes. It may be an option if you have not taken diabetes drugs before or stopped them over three months ago, and your blood sugar and weight are in certain ranges.
This trial tests a combination of three diabetes medicines to see if they can quickly get high blood sugar under control in people newly diagnosed with type 2 diabetes. It's designed for those whose HbA1c is 9.0% or higher.
This trial is testing a combination of three diabetes medicines (henagliflozin, retagliptin, and metformin) in people newly diagnosed with type 2 diabetes. The goal is to see if this triple therapy works better for controlling blood sugar compared to standard treatments.
This study looks at the safety and effectiveness of adding a third oral diabetes medicine to your current two-drug combination. It is for adults with type 2 diabetes whose blood sugar is not well controlled on metformin plus one other pill.
Hear when a new Diabetes Mellitus trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.