PUFFINS brain health study for adults 50+
Part of Brain & nervous system, Heart & circulation clinical trials.
This study looks at how small blood vessel changes in the brain (called 'small vessel disease') affect thinking and memory over time. It may help us understand how to keep brains healthy as we age. If you are 50 or older and do not have any memory concerns, you might be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 50 years old or older.
- You should not have any current problems with your memory.
- You must have mild to moderate small vessel disease (visible on a brain scan).
- You need to be a suitable size for an MRI machine (not too large to fit comfortably).
- You must be able to read and speak English.
- You cannot have had a major stroke in the past (minor strokes or 'mini-strokes' are okay).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study follows people with cerebral small vessel disease (a condition where the small blood vessels in the brain are damaged) over time to learn more about how it progresses and how it affects people. Participating involves regular check-ins and MRI scans to monitor your health.
This study looks at whether certain deep brain veins seen on MRI are linked to thinking and memory problems in people with small-vessel brain disease. It compares brain scan findings with cognitive (thinking) testing to better understand what may drive cognitive dysfunction.
This study tracks people with cerebral small vessel disease (changes in the brain's tiny blood vessels) to learn more about how the condition progresses. It may be a good fit if you are 50 or older and have had an MRI showing these changes.
This study builds a brain imaging biobank for people with “small blood vessel disease” seen on MRI. Your MRI results can help researchers better understand these changes and track new events over time.
This study looks at brain scans and eye/eye-nerve findings to understand why thinking can change with aging. It may help researchers connect eye and brain changes, which could guide future ways to prevent or detect dementia early.
This study watches how small blood vessels in the brain change over time. It may help doctors understand brain health as people age.
Hear when a new Cerebral Small Vessel Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.