Testing a new antidepressant combination for depression
Part of Mental health clinical trials.
This study tests a new combination of two medications (dextromethorphan and bupropion) as a treatment for major depressive disorder. It may be an option if you have not already tried many antidepressants that didn't work.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with major depressive disorder (MDD) and your current depressive episode has lasted at least 4 weeks.
- You have not tried 2 or more different antidepressants that did not work for your current depression.
- You are not currently at risk of harming yourself or others.
- You do not have a history of seizures, eating disorders, or uncontrolled high blood pressure.
- You are not allergic to bupropion, dextromethorphan, or related medications.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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