Treating stroke beyond 24 hours with artery-opening procedure
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests whether opening a blocked large artery in the brain up to 5 days (or even 7 days if symptoms are worsening) after a stroke can improve outcomes. It uses a catheter-based treatment (endovascular therapy) for people who have not responded to standard care and have limited brain damage so far.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your stroke symptoms started between 24 hours and 5 days ago (or up to 7 days if symptoms were getting worse).
- Your stroke symptoms are rated moderate to moderately severe (NIHSS score 5–25).
- Brain scans show a severe blockage (70% or more) in the carotid or middle cerebral artery, but the stroke damage is not too extensive.
- You have not had a prior stroke that left you with significant disability (mRS score less than 2).
- You do not have conditions that increase bleeding risk, like low platelets, blood thinner use with high INR, or recent bleeding in the brain.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This trial tests whether combining local cooling with a procedure to reopen blocked arteries can help people who have had a severe stroke with a large area of brain damage. It looks at patients who can be treated within 24 hours of symptoms starting.
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This trial tests a specialized clot-removal treatment for people who had a mild but disabling stroke up to 24 hours ago and have a large artery blockage in the brain. The goal is to see if this precision therapy can help reduce disability and improve recovery.
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