Clin2
NCT06967480Possibly a fitRecruiting

Early ravulizumab for recent-onset generalized myasthenia gravis

Generalized Myasthenia GravisAnti-AChR Antibody Positive

Treatments studied

Part of Brain & nervous system, Cancer, Immune system & allergy clinical trials.

This trial tests an early treatment with ravulizumab (a medication that blocks part of the immune system) for people who have recently developed moderate-to-severe generalized myasthenia gravis. The goal is to see if starting treatment early can improve symptoms and daily life.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
40 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You must have a confirmed diagnosis of generalized myasthenia gravis with anti-AChR antibodies.
  • Your MG symptoms started within the last 3 years.
  • Your MG is moderate to severe (MGFA class IIb, III, or IV).
  • You cannot have been treated before with ravulizumab or similar C5 inhibitors.
  • You must be vaccinated against meningitis (or take preventive antibiotics) at least 2 weeks before starting treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07596784Recruiting· Phase 3
Ravulizumab for Generalized Myasthenia Gravis in Chinese Adults

This trial tests whether ravulizumab, a medication that blocks part of the immune system, can improve muscle weakness and fatigue in people with generalized myasthenia gravis (gMG). The study focuses on Chinese adults who have moderate-to-severe MG symptoms despite current treatments.

Beijing
NCT07221838Recruiting· Phase 4
Steroid Tapering Study for Myasthenia Gravis on Ravulizumab

This study is for people with generalized myasthenia gravis who are already on ravulizumab and a daily steroid. It aims to see if the steroid dose can be safely lowered over time.

Chicago, Illinois
NCT07570589Recruiting
Tracking myasthenia gravis symptoms on rozanolixizumab treatment

This study follows patients with generalized myasthenia gravis (a condition where muscles weaken over time) who have specific antibodies and are being treated with rozanolixizumab, a medication that helps reduce symptom severity. Researchers will monitor how symptoms change in real-world settings.

Nice, Alpes-maritimes
NCT07622342Not yet recruiting· Phase 2
Study of a new injection for myasthenia gravis

This trial tests an investigational drug called SHR-2173, given as an injection, for people with generalized myasthenia gravis. It aims to see if the drug can improve muscle strength and daily function.

Changsha, Hunan
NCT06607627Recruiting· Phase 3
Testing gefurulimab in children with generalized myasthenia gravis

This study tests a new drug called gefurulimab in children and teens with generalized myasthenia gravis (a disease that causes muscle weakness). It looks at how safe and effective the drug is, and how it works in the body.

Washington D.C., District of Columbia
NCT06193889Recruiting· Phase 2/Phase 3
Car-t cell therapy for generalized myasthenia gravis

This trial tests a new cell therapy (CAR-T cells) for people with generalized myasthenia gravis. It aims to reduce symptoms and improve daily life by targeting and destroying faulty immune cells.

Los Angeles, California

Hear when a new Generalized Myasthenia Gravis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.