Clin2
NCT06976476Possibly a fitRecruiting

IgPro20 to prevent infections in multiple myeloma patients on bispecific therapy

Multiple MyelomaHypogammaglobulinemiaHypogammaglobulinemia, Acquired

Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.

This study tests whether a weekly infusion of a blood product called IgPro20 can help prevent infections in people with multiple myeloma who are already being treated with a bispecific antibody. If you qualify, you will receive the study treatment and be monitored for safety and infection rates.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have multiple myeloma that is relapsed or refractory and you are currently receiving a bispecific antibody.
  • You have received between 2 and 4 cycles of that bispecific antibody therapy.
  • You are 18 years or older and your performance status is good (ECOG 0-3).
  • You have not had a stem cell transplant within the last 3 months, and you are not planning CAR-T therapy in the next 6 months.
  • You do not have active HIV, hepatitis B or C, and you have not had more than one serious infection in the last 3 months.
  • You do not have other active cancers, a known allergy to immunoglobulin, significant kidney issues, or certain metabolic disorders.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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