Clin2
NCT06980142Possibly a fitNot yet recruiting

CM512 for moderate-to-severe COPD

Chronic Obstructive Pulmonary Disease

Treatments studied

Part of Lungs & breathing clinical trials.

This study tests a new medication called CM512 for people with moderate-to-severe COPD who still have flare-ups despite using their regular inhalers. It aims to see if adding this treatment can reduce flare-ups and improve quality of life.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
204 people
Ages
40 years to 80 years
Study type
Interventional

Who can take part

  • You are between 40 and 80 years old.
  • You have been diagnosed with COPD for at least 1 year.
  • You have had at least 2 moderate flare-ups or 1 severe flare-up in the past year.
  • You have been using a COPD inhaler (either triple therapy or two medicines) for at least 3 months.
  • You are a current or former smoker with a smoking history of at least 10 pack-years.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06547333Not yet recruiting· Phase 2/Phase 3
Study of CM310 for frequent COPD flare-ups

This study tests a new injectable medicine called CM310 for people with moderate to severe COPD who have chronic bronchitis and frequent flare-ups, despite using standard inhalers. It aims to see if CM310 can reduce flare-ups and improve breathing by targeting a specific type of inflammation.

NCT07418736Recruiting· Phase 2
CM326 for moderate to severe COPD

This trial tests a new medicine called CM326 for people with moderate to severe COPD. It aims to see if the drug can reduce flare-ups and improve lung function.

Beijing, Beijing Municipality
NCT04664491Recruiting
Program to reduce COPD flare-ups with standardized care

This study tests whether a structured care program for COPD can lower how often your symptoms flare up. It may help by improving everyday management and preventing future worsening.

Beijing, Beijing Municipality
NCT07190222Recruiting· Phase 3
New medicine for COPD with frequent flare-ups

This study tests a new medicine called Lunsekimig for people with COPD that has frequent flare-ups and high eosinophil levels (a sign of inflammation). It aims to see if it can help control symptoms better than a placebo (a dummy treatment).

Birmingham, Alabama
NCT07349524Recruiting· Phase 2
A study of an oral tablet for COPD

This study tests an oral tablet called RSS0343 for people with moderate to severe COPD. It aims to see if the tablet can improve lung function and reduce flare-ups when added to your current breathing treatments.

Guangzhou, Guangdong
NCT07011524Recruiting· Phase 2
Study of CM512 injection for moderate-to-severe asthma

This trial tests a new injection, CM512, for people with moderate-to-severe asthma that is not well controlled with current inhalers. It aims to see if the treatment can reduce asthma attacks and improve symptom control.

Guangzhou, Guangdong

Hear when a new Chronic Obstructive Pulmonary Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.