Clin2
NCT06981806Possibly a fitNot yet recruiting

Two new drugs for advanced pancreatic cancer

Metastatic Pancreatic Ductal Adenocarcinoma

Part of Cancer clinical trials.

This study tests two new drugs (cosibelimab and balixafortide) given together to see if they can help people with advanced pancreatic cancer that has not responded to standard chemotherapy. The goal is to find a safe and effective treatment option for this difficult-to-treat cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
24 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must have advanced pancreatic cancer that has spread or cannot be surgically removed, and it must have progressed after standard chemotherapy.
  • You must have a performance status (ECOG) of 0-2, meaning you are generally able to care for yourself, though you may need some help.
  • You must not have had prior treatment with certain immunotherapy drugs (like PD-1, PD-L1, or CTLA-4 inhibitors).
  • You must not have active or recent lung inflammation that required steroids, and no active autoimmune disease requiring immunosuppressive treatment in the past 2 years.
  • You must not have untreated brain metastases, active infections, or have received a live vaccine within 30 days.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06843551Recruiting· Phase 2
Testing a new immunotherapy combo for advanced pancreatic cancer

This trial is testing two immunotherapy drugs (balstilimab and botensilimab) to see if they can shrink tumors in people with advanced pancreatic cancer that has worsened after at least one prior treatment. If you have microsatellite stable (MSS) disease, you may be eligible.

Miami, Florida
NCT07165951Recruiting· Phase 3
Study of new drug combo for first treatment of advanced pancreatic cancer

This trial tests a new combination of drugs (TQB2868 injection plus anlotinib capsules) compared to standard chemotherapy for people with pancreatic cancer that has spread to other parts of the body and has not been treated before.

Hefei, Anhui
NCT07733050Not yet recruiting· Phase 2
Second-line treatment for advanced pancreatic cancer

This trial tests a combination of three drugs (serplulimab, bevacizumab, and a chemotherapy regimen) for people with pancreatic cancer that has spread or cannot be removed. It is for those who have already had one prior treatment and aims to see if this new combination can help control the cancer.

Shanghai, Shanghai Municipality
NCT07490301Recruiting· Phase 2/Phase 3
Study of a new drug combo for first-line metastatic pancreatic cancer

This trial tests a new targeted drug, telisotuzumab adizutecan, combined with standard chemotherapy (FOLFOX) for people with advanced pancreatic cancer that has spread. The goal is to see if this combination works better than current treatments.

New Haven, Connecticut
NCT07595172Recruiting· Phase 1/Phase 2
New drug combination for advanced pancreatic cancer

This study tests whether combining three treatments—NALIRIFOX (chemotherapy), Adebrelimab (an immune-boosting antibody), and PULSAR (radiation)—can help people with advanced pancreatic cancer that hasn't been treated before. The goal is to see if this combination works better than standard care.

Chengdu, Sichuan
NCT07578337Not yet recruiting· Phase 2
New treatment for advanced pancreatic cancer

This study tests a new treatment for people with stage 4 pancreatic cancer who haven't yet had any treatment for advanced disease. The goal is to see if the new treatment can help shrink or control the cancer.

Zaragoza, Aragon

Hear when a new Metastatic Pancreatic Ductal Adenocarcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.