New drug combo for advanced pancreatic cancer after first treatment
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a combination of two targeted drugs (serplulimab and bevacizumab) plus two different chemotherapy regimens for people with advanced pancreatic cancer that has worsened after first-line treatment. The goal is to see if this new combination can help shrink tumors or slow the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced pancreatic cancer that has spread and you've already had one round of chemotherapy.
- You have never been treated with irinotecan or oxaliplatin (types of chemo drugs).
- You have not had immunotherapy (like PD-1 or PD-L1 inhibitors) or anti-angiogenic therapy (like Avastin) before.
- Your tumor is not invading a major blood vessel and you don't have a high risk of bleeding.
- Your overall health is good enough to be up and about (ECOG score 0-1) and you have no uncontrolled medical conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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