Clin2
NCT06982274Possibly a fitRecruiting

Arsenic and ATRA for new APL patients

Acute Promyelocytic Leukemia (APL)

Part of Blood & lymphatic, Cancer clinical trials.

This trial tests a combination of oral arsenic and ATRA for people newly diagnosed with acute promyelocytic leukemia (APL). It aims to see if this drug combo can treat the disease effectively without standard chemotherapy.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
115 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • Must be newly diagnosed with APL (a type of leukemia) and confirmed by genetic testing
  • Age between 18 and 75 years old
  • Good liver and kidney function (based on blood tests)
  • Women must be postmenopausal, have had surgery to prevent pregnancy, use highly effective birth control, or have a partner who had a vasectomy
  • No other active cancer or serious heart, lung, or liver conditions

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07296445Not yet recruiting· Phase 3
Oral vs IV arsenic trioxide for standard-risk APL

This trial is comparing an oral (pill) form of arsenic trioxide to the standard IV (drip) form. If you have already completed initial therapy for your type of leukemia and are in remission, this study could help you take your medicine as a pill instead of through a needle.

NCT07504458Recruiting· Phase 3
Study of QTX-2101 for adults with a type of leukemia

This trial tests a new drug, QTX-2101, in people with acute promyelocytic leukemia (APL) that is low- or intermediate-risk. The study aims to see if the drug works and is safe for those who qualify.

Birmingham, Alabama
NCT07503730Recruiting· Phase 3
Early use of realgar-indigo naturalis formula plus ATRA for APL patients

This trial tests whether giving a combination of two oral medicines—realgar-indigo naturalis formula (RIF) and all-trans retinoic acid (ATRA)—early in treatment can help people with acute promyelocytic leukemia (APL), a specific type of blood cancer. The goal is to see if this approach works better than current standard care.

Xi'an, Shaanxi
NCT01409161Recruiting· Phase 2
Tretinoin and arsenic drugs for newly diagnosed acute promyelocytic leukemia

This trial studies how well a combination of tretinoin (ATRA) and arsenic trioxide (ATO)—with or without another antibody-like drug called gemtuzumab—treats people with newly diagnosed acute promyelocytic leukemia (APL). The goal is to see if these medicines work better together and are safe.

Houston, Texas
NCT04793919Recruiting· Phase 2
Study of new treatment for youth with acute promyelocytic leukemia

This Phase 2 study tests a treatment approach for children and teens newly diagnosed with acute promyelocytic leukemia (APL) that is confirmed by a specific lab genetic change. It may help improve outcomes, but it requires meeting several safety and test-confirmation criteria.

Brussels
NCT04897490Recruiting
Real-world study of ATO plus ATRA for adult acute APL

This study looks at how well first-time treatment with ATO plus ATRA works in adults with acute promyelocytic leukemia (APL). It mainly checks treatment results in real life, including whether patients reach “molecular remission” (very deep disease control).

La Plata, Buenos Aires

Hear when a new Acute Promyelocytic Leukemia (APL) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.