Comparing oral vs. IV arsenic trioxide for newly diagnosed APL
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests whether an oral version of arsenic trioxide works as well as the IV version for people with a certain type of leukemia called APL. It aims to confirm that taking the drug by mouth has similar safety and effectiveness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have newly diagnosed, low-risk APL with a white blood cell count at diagnosis of 10,000 cells/µL or lower.
- You must have completed your first round of treatment (induction) with arsenic trioxide and ATRA and be in complete remission with normal blood counts.
- You must be in good enough health to have a life expectancy of at least 9 months.
- Your heart's electrical activity (QT interval on an EKG) must be within normal limits—450 milliseconds or less for men, 460 ms or less for women.
- You should not have any stomach or intestine problems that would affect how you absorb oral medicine, and you must be able to swallow pills.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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