Letrozole plus hormone therapy for adenomyosis in IVF
Part of Women’s health & pregnancy clinical trials.
This trial tests whether adding letrozole (a medication that lowers estrogen) to standard hormone therapy helps women with adenomyosis have a better chance of pregnancy during in vitro fertilization (IVF). If you have adenomyosis and are planning an IVF cycle with one embryo transfer, this study may be a good fit.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with adenomyosis using a vaginal ultrasound (a wand-like device inserted into the vagina to see the uterus).
- You do not have uterine fibroids, abnormal uterine shapes, or other uterine issues like polyps or fluid.
- You have not had any previous uterine surgeries (C-section is okay).
- You do not have any untreated bleeding or hormonal conditions.
- Your partner’s sperm test does not show severe problems, and you plan to have only one embryo transferred.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether adjusting the length of pre-treatment with a hormone blocker (GnRH agonist) and adding letrozole before a frozen embryo transfer can improve pregnancy outcomes for people with adenomyosis.
This trial tests if the drug nintedanib can improve pregnancy rates in women with adenomyosis who are undergoing IVF. It is for women who have at least one high-quality frozen embryo and want to see if this medication helps the embryo implant successfully.
This trial looks at whether frozen embryo transfer can help women with adenomyosis (a condition where the inner lining of the uterus grows into its muscle wall) who have trouble getting pregnant. It aims to understand if this method improves pregnancy chances.
This study tests whether using a hormone medication (GnRH agonist) before a frozen embryo transfer helps women with adenomyosis. If you have adenomyosis and are planning a frozen embryo transfer, this trial will help compare results with or without the pre-treatment.
This trial compares two ways to prepare the uterus for a frozen embryo transfer: using the hormone letrozole or a standard artificial cycle. The goal is to see which approach works better for people with irregular periods.
This trial tests a treatment for adenomyosis, a condition where the uterine lining grows into the muscle wall. It aims to help women with heavy bleeding, painful periods, or pelvic pain.
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