Comparing an experimental drug to standard chemo for ovarian cancer
Treatments studied
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This trial tests a new drug called BL-B01D1 against standard chemotherapy for people with ovarian cancer that no longer responds to platinum-based treatments. The goal is to see which option works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with ovarian, fallopian tube, or primary peritoneal cancer that has come back after platinum chemotherapy.
- You have had 1 to 3 previous treatments for your cancer, and the last one stopped working or caused side effects that were too severe to continue.
- Your doctor has confirmed that your cancer has a measurable tumor on a scan.
- You are well enough to be up and about (ECOG score 0 or 1) and have a life expectancy of at least 3 months.
- If you have a specific receptor called FR alpha on your cancer cells, you must have already tried a drug called mirvetuximab soravtansine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a new drug called IBI354 against standard chemotherapy for people with ovarian, primary peritoneal, or fallopian tube cancer that stopped responding to platinum-based treatments. It aims to see if the new drug works better and has fewer side effects.
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This trial tests an investigational drug called TORL-1-23 for people with ovarian cancer that has stopped responding to platinum chemotherapy. It aims to see if the drug can help shrink or control the cancer.
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This Phase 1/2 study tests BL-B01D1 in people with recurrent or metastatic gynecologic cancers (such as ovarian, uterine, or cervical cancer) when standard treatments have failed or aren’t options. It focuses on how well the drug works and whether it can be given safely.
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