Noninvasive breathing support for Guillain-Barré syndrome
Part of Brain & nervous system, Immune system & allergy clinical trials.
This trial tests whether noninvasive breathing support (like a mask or nasal prongs) can help people with Guillain-Barré syndrome who have trouble breathing. It aims to see if this approach can avoid the need for a breathing tube.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with Guillain-Barré syndrome using standard criteria.
- You have moderate breathing problems, such as low oxygen or high carbon dioxide levels, or rapid breathing.
- Your muscle strength and breathing scores are within specific ranges (Hughes Grade 3-4, EGRIS 1-3, MRC sum score 20-40).
- You are awake and alert (GCS 13 or higher), with a good cough and gag reflex, and stable blood pressure and heart rate.
- Your breathing symptoms started within the last 7 days.
- You do not have chronic lung disease (like COPD, asthma, or lung scarring) and do not immediately need a breathing tube.
- You are not pregnant and have no severe bulbar problems (trouble swallowing or speaking) or facial injuries that prevent using a mask.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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