Clin2
NCT06997081Possibly a fitRecruiting

ERd combination for newly diagnosed multiple myeloma

Multiple Myeloma

Treatments studied

Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.

This trial tests a combination of three drugs (elranatamab, lenalidomide, and dexamethasone) for people newly diagnosed with multiple myeloma. The goal is to see if this treatment can lead to a very deep response (no detectable cancer cells) in the bone marrow.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
104 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be newly diagnosed with multiple myeloma and have certain signs of the disease in your blood, urine, or bone marrow.
  • You need to have at least one sign that the myeloma is causing organ damage, like low red blood cells, kidney problems, or bone lesions.
  • You must be 18 years or older and have a good enough performance status to be up and about for at least half the day.
  • Your blood counts and organ function (kidney, liver) need to be within acceptable ranges.
  • You must agree to use effective contraception if you could become pregnant or get someone pregnant.
  • You cannot have received more than one cycle of prior myeloma treatment, and you must not have certain other serious medical conditions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05623020Recruiting· Phase 3
New treatment for newly diagnosed transplant-ineligible myeloma

This Phase 3 study compares a three-drug combination (elranatamab, daratumumab, and lenalidomide) versus a standard three-drug treatment (daratumumab, bortezomib, lenalidomide, plus dexamethasone). It aims to see which plan works better for people newly diagnosed with multiple myeloma who cannot get a stem cell transplant.

Jupiter, Florida
NCT07830485Not yet recruiting· Phase 2
Combination therapy for newly diagnosed multiple myeloma without stem cell transplant

This trial tests a combination of three drugs (CM336, daratumumab, and lenalidomide) for people with newly diagnosed multiple myeloma who are not eligible for a stem cell transplant. The goal is to see if this combination is safe and effective in controlling the disease.

Tianjin, Tianjin Municipality
NCT07247097Not yet recruiting· Phase 2
Comparing two drug combinations for newly diagnosed multiple myeloma

This trial tests two different drug combinations for people newly diagnosed with multiple myeloma who are not getting a stem cell transplant right away. It compares one drug (elranatamab) to another (daratumumab), both given with a standard three-drug regimen called RVd Lite, to see which works better.

Boston, Massachusetts
NCT07095452Recruiting· Phase 2/Phase 3
Newly diagnosed myeloma: comparing drug combinations for non-transplant patients

This trial tests a new combination of two drugs (etentamig and daratumumab) against the current standard of daratumumab plus lenalidomide and dexamethasone in people recently diagnosed with multiple myeloma who cannot have a stem cell transplant. The goal is to see which combination better controls the disease while keeping side effects manageable.

Scottsdale, Arizona
NCT05581875Not yet recruiting· Phase 1/Phase 2
Combination therapy for multiple myeloma after one prior treatment

This trial tests a new combination of drugs for people with multiple myeloma whose cancer did not respond to or returned after one prior treatment with lenalidomide. The goal is to see if this combination is safe and effective.

NCT07764861Not yet recruiting· Phase 2
Study of new treatment for multiple myeloma

This study tests an investigational drug for people with multiple myeloma, a type of blood cancer. It aims to see how safe and effective the treatment is for patients who are newly diagnosed or have relapsed after prior therapy.

Beijing, Beijing Municipality

Hear when a new Multiple myeloma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.