Fecal transplant for children with hard-to-treat nephrotic syndrome
Treatments studied
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests if fecal microbiota transplantation (a transfer of healthy gut bacteria) can help children whose nephrotic syndrome does not respond well to steroids. It aims to reduce steroid dependence or resistance.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 2 and 18 years old.
- You have nephrotic syndrome that is steroid-dependent or steroid-resistant.
- Your steroid dose for dependency is less than 0.5 mg per kg each day.
- You do not have any other active infections or major organ problems.
- Your kidney function is normal.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether transplanting healthy gut bacteria can help children whose bodies are rejecting donor stem cells in their intestines and who haven't responded to high-dose steroids. The goal is to reduce intestinal damage and improve outcomes after bone marrow transplant.
This trial tests whether transferring stool microbes (called fecal microbiota transplantation, or FMT) can improve Crohn’s disease in children who have not gotten better with usual treatments. If you qualify, the study will check symptoms and colon imaging/score changes over the study follow-up.
This study tests if a fecal transplant (transferring healthy bacteria from a donor's stool into your gut) can help people with severe gut graft-versus-host disease that hasn't responded to steroids. It's for patients who have had a stem cell transplant and now have ongoing, severe gut symptoms.
This trial tests whether rituximab works as well as mycophenolate in children whose nephrotic syndrome (kidney condition) comes back when steroid medicines are reduced. It aims to find the safest and most effective option during a relapse.
This trial studies whether transferring healthy stool bacteria into the gut (fecal microbiota transplantation, or FMT) can improve symptoms in children with ulcerative colitis. It may help by changing gut bacteria, especially for children who are newly diagnosed or who didn’t respond to standard treatments.
This study tests whether transplanting healthy donor stool into the gut can help children and young adults with ongoing digestive issues after a stem cell transplant. It may improve symptoms like diarrhea or the need for feeding tubes.
Hear when a new Steroid-Resistant Nephrotic Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.