CPPD joint disease study for acute and chronic forms
Part of Bones, joints & muscles, Skin clinical trials.
This study looks at calcium pyrophosphate deposition (CPPD) disease, a condition where crystals build up in joints and cause pain and swelling. It aims to learn more about how the disease acts in both sudden attacks and long-term joint problems, which could help improve treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- For chronic CPPD: You must be at least 65 years old.
- You must have a CPPD diagnosis confirmed by a rheumatologist using specific criteria.
- Your kidney function must be at least 30 ml/min/1.73m2 (based on a blood test).
- You must have had active joint symptoms for at least 3 months, like ongoing pain or at least one flare-up in the past 3 months.
- If you have had a first acute CPPD attack and were part of an earlier study (COLCHICORT), you may qualify for the retrospective part.
- You must stop certain arthritis medications for a period before joining (e.g., 2 weeks for anti-inflammatories, 1 month for methotrexate).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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