Tocilizumab for chronic CPPD arthritis pain
Treatments studied
Part of Bones, joints & muscles clinical trials.
This trial tests if tocilizumab can help people with chronic pain from CPPD crystal arthritis (also called pseudogout). It is for people whose pain has not responded to usual treatments like colchicine, NSAIDs, or steroids.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have been diagnosed with CPPD (pseudogout) using the latest criteria
- You have had persistent joint pain for more than 3 months or have frequent attacks
- You have at least 4 painful joints and your overall pain is moderate to severe
- You have tried or cannot use common treatments like colchicine, NSAIDs, steroids, or anakinra
- You are willing to use effective birth control if you could become pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at calcium pyrophosphate deposition (CPPD) disease, which causes joint inflammation. It aims to understand the disease better by studying people with either an acute first episode or ongoing chronic CPPD arthritis.
This study tests if baricitinib, an anti-inflammatory pill, can help people with arthritis caused by CPPD crystals (also called pseudogout). It is for people aged 55 and older who have swelling in their hands/wrists or large joints.
This study looks at people with certain types of crystal deposits in joints (like gout, CPPD, or hydroxyapatite crystal disease). It uses scans such as ultrasound and a special CT-type scan called DECT to confirm and better understand what’s causing your symptoms.
This trial tests the drug tocilizumab (Actemra) to see if it helps reduce swelling in the aorta in people with giant cell arteritis (GCA) who are newly diagnosed or have had a flare. It may offer a targeted treatment for aortitis without using high-dose steroids.
This trial tests if colchicine can reduce pain and swelling in people with CPPD (calcium pyrophosphate deposition disease), a type of arthritis. If you have had a swollen, red, or warm joint in the last 3 months and your pain is moderate or higher, this study may offer a possible treatment.
This trial tests a drug called tocilizumab (an IL-6 blocker) for people with calciphylaxis, a painful skin condition linked to kidney disease. The goal is to see if the drug can reduce inflammation and improve skin sores.
Hear when a new Calcium Pyrophosphate Deposition Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.