Clin2
NCT07007962Possibly a fitRecruiting

Oral pill for immune thrombocytopenia after first treatment fails

Immune Thrombocytopenia

Treatments studied

Part of Blood & lymphatic, Immune system & allergy clinical trials.

This trial tests an oral medicine called rilzabrutinib for adults with immune thrombocytopenia (ITP) whose first treatment stopped working or who need steroids long-term. The goal is to see if it helps raise platelet counts and reduce bleeding risk.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
60 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older with a confirmed diagnosis of primary ITP (not caused by another condition)
  • You have had at least one standard first treatment for ITP and it worked for a while
  • Your ITP has come back, you no longer respond to treatment, or you are dependent on steroids
  • You have not had your spleen removed and have not received advanced therapies like rituximab or fostamatinib
  • You do not have another bleeding disorder, cancer in the last 5 years (except non-melanoma skin cancer), or a history of organ transplant

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07315373Not yet recruiting· Phase 1
Finding the right dose of zanubrutinib for new immune thrombocytopenia

This trial tests an oral medication called zanubrutinib to find the best dose for adults newly diagnosed with immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, leading to low counts and bleeding risk. It may offer a new treatment option for those who haven't had any prior therapy.

NCT05214391Recruiting· Phase 2
Zanubrutinib for chronic immune low platelets after prior treatments

This Phase 2 study looks at zanubrutinib, a new medication, in people with immune thrombocytopenia (ITP) whose low platelet count has lasted more than 3 months and has not responded to prior steroid and other treatments. It may help raise platelets and reduce bleeding risk when other therapies have not worked.

Tianjin, Tianjin Municipality
NCT07234019Recruiting· Phase 2
Rituximab plus anti-CD38 antibody for ITP

This trial tests whether adding an anti-CD38 antibody to the standard drug rituximab works better than rituximab alone for adults with long-term immune thrombocytopenia (ITP) who have already tried steroids without lasting success.

Tianjin, Tianjin Municipality
NCT07297563Recruiting· Phase 2
Anti-CD38 antibody vs rituximab for hard-to-treat ITP

This trial tests a new antibody drug (anti-CD38) compared to a standard drug (rituximab) for adults with ITP that hasn't responded well to steroids. The goal is to see if the new drug works better at raising platelet counts and reducing bleeding risk.

Tianjin, Tianjin Municipality
NCT06519565Recruiting· Early Phase 1
Testing PRG-1801 for hard-to-treat immune thrombocytopenia

This early-phase trial tests an investigational cell therapy called PRG-1801 for people with immune thrombocytopenia (ITP) that hasn't responded to or has come back after standard treatments. It aims to see if PRG-1801 can safely help raise platelet counts.

Wuhan, Hubei
NCT07362199Recruiting· Phase 2
New combo treatment for chronic ITP

This trial tests combining two antibodies (anti-CD38 and rituximab) for adults with chronic ITP who haven't been helped by steroids or other standard treatments. The goal is to see if this drug pair can raise platelet counts and reduce bleeding risk.

Tianjin, Tianjin Municipality

Hear when a new Immune Thrombocytopenia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.