Rituximab plus anti-CD38 antibody for ITP
Treatments studied
Part of Blood & lymphatic, Immune system & allergy clinical trials.
This trial tests whether adding an anti-CD38 antibody to the standard drug rituximab works better than rituximab alone for adults with long-term immune thrombocytopenia (ITP) who have already tried steroids without lasting success.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have been diagnosed with ITP for at least 3 months.
- Your platelet counts have been below 30 (×10⁹/L) in the last 48 hours and also in two separate tests at least one week apart during screening.
- You have tried steroid treatment for ITP and it either didn't work, stopped working, or you relapsed.
- You have not had emergency ITP treatment (like IV steroids, platelets, or gamma globulin) in the last 2 weeks.
- Your liver and kidney function tests are within 1.5 times the normal upper limit.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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