Clin2
NCT07010029Possibly a fitRecruiting

Heart vein device for angina with no blocked arteries

Angina With No Obstructive Coronary Artery DiseaseANOCACoronary Sinus Reducer

Part of Heart & circulation, Pain clinical trials.

This trial tests a special device placed in a vein of the heart to help patients who have chest pain (angina) but no major blockages in their heart arteries. It is designed for people who have tried maximum medications but still have symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
50 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have chest pain that is stable (not getting worse fast).
  • Your heart arteries have no significant blockages (less than 50% narrowing or up to 70% with good flow).
  • An invasive test has confirmed small vessel disease in your heart.
  • You have been on the maximum dose of heart medications for at least 3 months with no other options left.
  • You do not have certain other heart conditions like severe valve disease, heart muscle disease, or a recent heart attack (within the last 6 months).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07485985Not yet recruiting
A device to reduce chest pain when other treatments are not possible

This trial tests a small device called a coronary sinus reducer that is placed in a vein of the heart to improve blood flow and reduce chest pain in people who still have angina despite medications and cannot have stents or bypass surgery. The procedure is done through a small tube in the groin or arm.

NCT04606459Recruiting
Device trial for hard-to-treat heart chest pain from small vessels

This trial tests whether a small pressure-reducing device placed in a heart vein (the coronary sinus) can reduce symptoms in people with ongoing chest pain from tiny blood vessel problems. It is for angina that has not improved despite standard heart medicines, and only if special heart tests show reversible reduced blood flow.

Mainz, Rhineland-Palatinate
NCT06898541Enrolling by invitation
A device to treat chest pain from small heart artery disease

This trial tests a device called the Coronary Sinus Reducer for people with chest pain caused by problems in the small arteries of the heart. The device is placed in a vein near the heart to improve blood flow and reduce symptoms.

Rotterdam
NCT01566175Recruiting
Neovasc device trial for hard-to-treat chest pain

This trial tests a device called the Neovasc Coronary Sinus Reducer to help people with long-lasting, hard-to-control chest pain (angina) who cannot have artery-opening procedures. It may improve symptoms by changing blood flow in the heart’s vein system.

Tel Aviv
NCT07057323Enrolling by invitation
Coronary sinus reducer for heart failure with preserved pumping function

This trial tests a device placed in a heart vein to improve symptoms in people whose heart pumps normally but still causes shortness of breath and fatigue. The device may help relieve pressure in the heart and improve daily life.

Rochester, Minnesota
NCT05102019Recruiting
Device implant for severe angina using a coronary sinus reducer

This trial tests whether implanting a small device in the heart’s coronary sinus can reduce symptoms in people with long-lasting “refractory” angina despite taking the usual heart medicines. It may help improve how much activity you can do and reduce angina-related limitations.

Phoenix, Arizona

Hear when a new Angina With No Obstructive Coronary Artery Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.