Device trial for hard-to-treat heart chest pain from small vessels
Treatments studied
Part of Heart & circulation, Pain clinical trials.
This trial tests whether a small pressure-reducing device placed in a heart vein (the coronary sinus) can reduce symptoms in people with ongoing chest pain from tiny blood vessel problems. It is for angina that has not improved despite standard heart medicines, and only if special heart tests show reversible reduced blood flow.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old
- You have long-term chest pain (angina) that is not controlled with usual heart medicines
- Your tests show “reversible” reduced blood flow to the heart (not fixed, one-time damage)
- Your heart’s tiny-vessel problem is confirmed by an invasive test (either IMR >25 and/or CFR <2.0 with FFR >0.8)
- You can understand the study and sign informed consent
- You can safely take required clot-preventing medicines (dual antiplatelet therapy)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a device called the Coronary Sinus Reducer for people with chest pain caused by problems in the small arteries of the heart. The device is placed in a vein near the heart to improve blood flow and reduce symptoms.
This trial tests a device called the Neovasc Coronary Sinus Reducer to help people with long-lasting, hard-to-control chest pain (angina) who cannot have artery-opening procedures. It may improve symptoms by changing blood flow in the heart’s vein system.
This trial tests whether implanting a small device in the heart’s coronary sinus can reduce symptoms in people with long-lasting “refractory” angina despite taking the usual heart medicines. It may help improve how much activity you can do and reduce angina-related limitations.
This registry study collects information from adults with microvascular angina (chest pain from small blood vessels in the heart). It may help researchers better understand how to assess and manage this condition over time.
This trial tests a small device called a coronary sinus reducer that is placed in a vein of the heart to improve blood flow and reduce chest pain in people who still have angina despite medications and cannot have stents or bypass surgery. The procedure is done through a small tube in the groin or arm.
This trial tests a device placed in a heart vein to improve symptoms in people whose heart pumps normally but still causes shortness of breath and fatigue. The device may help relieve pressure in the heart and improve daily life.
Hear when a new Coronary Microvascular Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.