Gut bacteria transplant for fast-progressing ALS
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial tests whether a transplant of healthy gut bacteria (called a microbiome transplant) can slow down ALS in people whose disease is progressing rapidly. It aims to see if changing the gut environment can help with symptoms and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a definite ALS diagnosis, and your disease is progressing quickly (a drop of 1.5 or more points per month on the ALSFRS-R scale).
- You are at least 18 years old.
- Your ALS symptoms are moderate (ALSFRS-R score of 24 or higher), and you can swallow capsules.
- You have been on a stable dose of riluzole, edaravone, or tofersen for at least 30 days, or you are not taking any of these and don't plan to during the study.
- You have not taken antibiotics in the last 3 months, probiotics or herbal supplements in the last 2 weeks, or any other investigational drug in the last 30 days.
- You are not pregnant, and if sexually active, you agree to use contraception.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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