Clin2
NCT07018388Possibly a fitEnrolling by invitation

Comparing two brain targets for non-invasive stimulation in Parkinson's

Parkinson Disease

Part of Brain & nervous system clinical trials.

This study compares two areas of the brain (subthalamic nucleus and globus pallidus interna) for stimulation using a new non-invasive technique called tTIS. The goal is to see which area works better to improve Parkinson's symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
100 people
Ages
50 years to 85 years
Study type
Interventional

Who can take part

  • You have a confirmed diagnosis of Parkinson's disease.
  • Your Parkinson's is at a mild to moderate stage (Hoehn & Yahr stage 3 or less).
  • Your Parkinson's medications have been the same for the past four weeks and will stay the same during the trial.
  • You do not have other brain conditions like a past head injury.
  • You are not taking certain psychiatric medications (antipsychotics, antidepressants, or drugs that affect dopamine, besides Parkinson's drugs).
  • You have no metal implants in your head or chest (like a deep brain stimulator or pacemaker).
  • Your vital signs (e.g., blood pressure) are stable.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06383247Recruiting
Precision TMS for parkinson's motor symptoms

This trial tests a precise form of brain stimulation (called TMS) to see if it can improve movement problems like stiffness, slowness, or tremors in people with Parkinson's disease. Participants must have a stable medication routine and no metal implants or brain surgery history.

Hefei, Anhui
NCT06008717Not yet recruiting
Deep brain stimulation for early Parkinson's disease

This trial tests whether deep brain stimulation (a surgical treatment that uses electrical pulses to calm overactive brain areas) can help people in the early stages of Parkinson's disease. If you join, you'll get either the stimulation or a placebo (inactive) treatment, and the study will see if it improves your symptoms.

NCT07568067Recruiting
Accelerated Brain Stimulation for Parkinson's Disease

This trial tests a new type of brain stimulation (called temporal interference stimulation) targeted at specific brain regions to help improve Parkinson's disease symptoms. Researchers will use MRI imaging and behavioral assessments to see if this approach can reduce movement problems and improve quality of life.

Guangzhou, Guangdong
NCT05509842Not yet recruiting
Fast brain stimulation for freezing of gait in Parkinson's disease

This study tests a new type of brain stimulation that may help people with Parkinson's disease who experience freezing of gait (when your feet feel stuck to the floor). It uses a non-invasive technique called transcranial magnetic stimulation (TMS) that sends magnetic pulses through the scalp to activate brain cells, without surgery.

Ann Arbor, Michigan
NCT07774312Recruiting
Comparing tTIS treatment intervals to standard care for Parkinson's

This study compares different schedules of a non-invasive brain stimulation treatment (called tTIS) to standard medication for Parkinson's disease. It aims to find the best timing for tTIS to improve motor symptoms.

Shanghai, Shanghai Municipality
NCT07625540Recruiting
Targeted Brain Stimulation for Parkinson's Motor and Non-Motor Symptoms

This trial tests a non-invasive brain stimulation technique (using electrical currents applied through the scalp) aimed at the subthalamic nucleus—a brain region involved in movement control—to help reduce both movement-related symptoms (like tremor and stiffness) and non-movement symptoms (like mood and sleep problems) in people with Parkinson's disease.

Shanghai, Shanghai Municipality

Hear when a new Parkinson Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.