DDX41 gene study for families with cancer risk
Part of Blood & lymphatic, Cancer clinical trials.
This study looks at people and families who have changes in the DDX41 gene or similar genes that may increase the risk of cancer. By joining, you can help researchers learn more about these gene changes and how they affect health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be older than 1 month.
- You have a change in the DDX41 gene, its RNA, or protein (or a similar gene change).
- If you don't have a gene change, you must have a close family member (parent, sibling, child, grandparent, grandchild, aunt, uncle, niece, nephew) who has a known or suspected gene change.
- You must have a doctor outside of the study who is managing your medical care.
- You (or your parent or guardian) must agree to sign a consent form to participate.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study follows people who have a known or suspected RUNX1 gene variant linked to FPDMM-like features. It may help improve understanding of the gene, and participants may contribute samples that researchers use for genetic testing and research.
This study looks at people who have rare or unusual cancers or who may have an inherited (family) risk for cancer. It helps researchers learn what genetic or other factors might be involved by collecting family history and medical records, including pathology slides.
This study follows people affected by DICER1-related tumors (and sometimes family members) to better understand how these conditions develop over time. It may help families by improving knowledge and guiding genetic counseling and future care.
This study looks at families where a blood cancer (hemopathy) may be linked to a change in the DDX41 gene. It tests family members to see if they have the same gene change, which can help understand hereditary risks.
This study uses advanced DNA testing to look for inherited gene changes in people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). It may help explain whether your illness could be part of a family-linked risk syndrome, which can guide treatment and family planning.
This trial studies whether certain inherited genes increase the risk of myeloid cancers or bone marrow failure. You will provide a DNA sample via a skin biopsy to look for these genetic changes.
Hear when a new Myelodysplastic Syndromes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.