Dapagliflozin after ICU discharge for heart and kidney health
Treatments studied
Part of Heart & circulation, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests if the drug dapagliflozin (a medicine that helps protect the heart and kidneys) can improve recovery in patients who needed a breathing machine or blood pressure support in the ICU. If you qualify, you would take the drug after leaving the ICU to see if it lowers the risk of heart or kidney problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You needed a breathing machine (ventilator) or strong blood pressure medication for more than 24 hours while in the ICU.
- Your doctor says you are ready to leave the ICU soon.
- You have a blood test showing either a certain level of a heart stress marker (NT-proBNP over 800 or BNP over 90) or your kidney function (eGFR) is between 25 and 90.
- You are not pregnant, not breastfeeding, and if you could become pregnant, you agree to use highly effective birth control during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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