Clin2
NCT06072326Possibly a fitNot yet recruiting

Dapagliflozin for kidney protection in type 1 diabetes

Type 1 Diabetes Mellitus With Diabetic Nephropathy

Treatments studied

Part of Hormones & metabolism, Immune system & allergy, Kidney & urinary, Women’s health & pregnancy clinical trials.

This trial tests a medication called dapagliflozin (often used in type 2 diabetes) to see if it can help protect the kidneys in people with type 1 diabetes who already have some signs of kidney damage. If it works, it could slow down further kidney decline.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
36 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You are between 18 and 64 years old.
  • You have had type 1 diabetes for at least 6 months.
  • Your urine shows a moderate amount of protein (albumin), which can be a sign of kidney stress.
  • Your kidney function (eGFR) is between 30 and 90, indicating mild to moderate kidney problems.
  • You are comfortable managing your insulin, including adjusting doses for meals and checking your blood sugar regularly.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06147232Not yet recruiting· Phase 2
Preventing kidney disease progression in type 1 diabetes with a new drug

This study tests whether a daily medication can slow down kidney damage in people with type 1 diabetes who already have some kidney problems. It may help protect your kidneys from getting worse.

Herlev
NCT05359263Recruiting· Phase 2
Dapagliflozin for kidney disease to improve heart structure

This Phase 2 study tests whether dapagliflozin can improve heart structure and function in people with chronic kidney disease (CKD). Dapagliflozin is a kidney-heart medicine that may affect how the heart changes over time, measured by heart scans.

Copenhagen
NCT07225465Not yet recruiting· Phase 2
Testing a safe dose of dapagliflozin for type 1 diabetes

This study tests a medication called dapagliflozin, which is usually for type 2 diabetes, to see if it can be used safely in people with type 1 diabetes. It focuses on preventing a serious side effect called ketoacidosis, where the blood becomes too acidic.

Fitzroy, Victoria
NCT06217302Recruiting· Phase 3
Sotagliflozin for kidney protection in type 1 diabetes

This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.

Stanford, California
NCT06398977Recruiting
Dapagliflozin to protect kidney function in dialysis patients

This trial tests whether a diabetes drug called dapagliflozin can help people on peritoneal dialysis keep their remaining kidney function longer. It is for patients who started dialysis recently and still make urine.

Chengdu, Sichuan
NCT06054035Recruiting· Phase 4
SGLT2 inhibitor for prediabetes complications

This trial tests if a drug called dapagliflozin (an SGLT2 inhibitor) can help prevent complications in people with prediabetes when added to lifestyle changes. It aims to see if this approach works better than lifestyle changes alone.

Berlin

Hear when a new Type 1 Diabetes Mellitus With Diabetic Nephropathy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.