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NCT05764057Possibly a fitRecruiting

Dapagliflozin to help the heart heal after a heart attack

AMISTEMINSTEMILeft Ventricular Dysfunction

Part of Heart & circulation clinical trials.

This trial tests whether dapagliflozin (a diabetes medicine also used for heart protection) can reduce harmful heart “remodeling” after an acute heart attack. It may help your heart function and structure recover over the following 6 months.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
450 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are age 18 or older.
  • Your heart attack was recent, and you had either STEMI or very high-risk NSTEMI, and you finished PCI or angiography.
  • Your heart pumping function is reduced (left ventricular ejection fraction of 45% or less).
  • Your kidney function is adequate (eGFR 25 or higher) and your blood pressure is not too low before starting (systolic over 100 and/or diastolic over 70).
  • You do not have an ongoing atrial fibrillation rhythm, and the study heart scans (echocardiogram) can be done clearly with your device situation.
  • You can sign consent and agree to be followed for 6 months, and you are covered by the French health system (AME not allowed).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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