Clin2
NCT07031999Likely a fitNot yet recruiting

Antibiotic-coated spacer for infected hip, knee, or shoulder replacements

Implant FailureInfection

Part of Infections clinical trials.

This trial tests a new type of temporary spacer that is coated with an antibiotic (vancomycin) to treat infections in hip, knee, or shoulder replacements. If you have an infected joint replacement, this spacer might help clear the infection and prepare the area for a new joint later.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
30 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years old or older.
  • You have an infected hip, knee, or shoulder replacement that needs to be removed.
  • You have signs of an active infection, like pain, fever, or drainage from the implant site.
  • You are willing to sign a consent form and attend follow-up visits for 6 months after surgery.
  • You are not pregnant or breastfeeding.
  • You do not have a severely weakened immune system (e.g., from certain transplants, untreated HIV, or long-term high-dose steroids).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06293352Recruiting
Comparing two antibiotic spacers for knee infection

This trial compares two types of antibiotic spacers for people with a long-term knee replacement infection. It tests whether a spacer made entirely of antibiotic cement or one with a metal core works better to treat the infection before a new knee replacement.

Chicago, Illinois
NCT07299591Recruiting
Antibiotic levels in hip infection spacer study

This study is testing a new way to measure how well antibiotics reach the infected area around a hip implant during a two-stage replacement surgery. If you are already planning this surgery, researchers want to see if the levels of antibiotics in the spacer are high enough to fight the infection.

Bonn, North Rhine-Westphalia
NCT07299565Recruiting
Knee infection trial: drug levels after spacer surgery

This trial studies how antibiotics reach the knee joint after a temporary antibiotic spacer is placed. It may help improve treatment for people having two-stage surgery for a knee prosthesis infection.

Bonn, North Rhine-Westphalia
NCT05169229Recruiting· Phase 2
Antibiotic bone graft to prevent infection in hip replacement

This trial tests whether adding antibiotics to the bone graft used during hip replacement surgery can lower the risk of infection. It may help people who need a bone graft as part of their hip replacement.

Linköping, Region Östergotland
NCT03713528Enrolling by invitation· Phase 4
Antibiotic placed in bone to help save an infected knee implant

This trial tests whether putting antibiotics directly inside the bone during surgery can improve outcomes for an infected knee prosthesis when the implant is being kept. It may help more people avoid needing full implant removal and replacement.

San Francisco, California
NCT06737809Recruiting
Silver-coated hip revision for infection

This trial tests a new silver-coated hip implant for people who need a revision due to a chronic infection around the joint. It may help control the infection while replacing the implant.

Berlin

Hear when a new Implant Failure trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.